Stahl's Illustrated Chronic Pain and Fibromyalgia by Stephen M. Stahl

Author:Stephen M. Stahl
Language: eng
Format: mobi
ISBN: 9780521133227
Publisher: Cambridge University Press
Published: 2009-09-13T21:00:00+00:00

Chronic Low-Back Pain

FIGURE 4.15. Back pain is one of the most common pain disorders, with 70-85% of all people having experienced back pain at some point in their lives. Obesity and tobacco usage are strong predisposing factors for lower back pain.

Chronic low-back pain, like osteoarthritis, does not derive from neuronal damage, but rather from spine or disc problems in the back. Central sensitization, however, can exacerbate this disorder, making non-opiate pain treatments helpful and often necessary.

Studies of pharmacological efficacy of norepinephrine versus serotonin reuptake inhibitors reveal that noradrenergic mechanisms are more effective at mitigating chronic low-back pain, particularly low doses of drugs with norepinephrine reuptake-inhibiting properties.

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